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Prof Alex Andrianopoulos

Laboratory Head
School of BioSciences
University of Melbourne

alex.a@unimelb.edu.au

Research Activities

We are studying a number of aspect of T. marneffei biology and pathogenicity and are particularly interested in understanding the molecular mechanisms which control the dimorphic switching and asexual development (conidiation) programs. Dimorphic switching is a temperature- and host-dependent response that allows T. marneffei to switch from a non-pathogenic hyphal growth form to the pathogenic yeast form. The yeast form is specialized to survive with host innate immune cells. Asexual development is the program the produce asexual spores, the infectious particles. We are teasing up the mechanisms that control these programs and examining their effects on growth and pathogenesis in the host.

Research Keywords

Researching in the following areas: Fungal pathogens, Innate immunity, Genomics, Animal Models - Zebrafish, Animal models - Mice

Techniques/Expertise

DNA-protein interactions, genomics, transcriptomics

Disease Models

Macrophage cells, zebrafish, mice

Genetically Modified Organisms

Talaromyces marneffei (formerly Penicillium marneffei), Aspergillus fumigatus, Aspergillus nidulans

Websites

biosciences.unimelb.edu.au/research/research-clusters/genetics-genomics-and-development/

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Prof Alex Andrianopoulos

Research Activities

Research Keywords

Techniques/Expertise

Disease Models

Genetically Modified Organisms

Websites

Other members with similar research interests

A/Prof Motti Gerlic

Prof Alister Ward

Dr Rebecca Gorrell

Dr Sara Klose

Dr Greg Moseley

Dr Tony Sadler

Prof Michael Hickey

Dr KE TANG

Dr Jim Harris

Adjunct Prof Kathryn Holt

Dr Hani Hosseini Far

Dr Simon Royce

Dr Alec Drew

A/Prof Mark Wright

Dr Kate Jeffrey

Prof A Richard Kitching

Prof Tim Stinear

Dr Kelly Wyres

Prof Paul Hertzog

Dr Amy Chung

Dr Douglas Gaskarth

Dr Kristie Jenkins

Dr Le Son Tran

Dr Rutger Roring

Ms Sarah Rosli

Dr Niamh Mangan

Dr Howard Yim

Dr Tom Brodnicki

Mrs Sheila Nankoberanyi

Dr Keith Al-Hasani

Dr Alison West

Dr Rhys Allan

Prof Bryan Williams

Dr Wenyi Li

Miss Kathryn Prame Kumar

Dr Dieter Bulach

Prof Bill Heath

Dr Grant Jenkin

Prof Di Yu

Ms Antara Ghoshal

Miss Rachel Peiris

Miss Michelle Clark

Ms Caitlin Rowe

Dr Helen Stoelting

Dr Jiyao Gan

Dr Latasha Abeynaike

A/Prof Mark Chong

Dr Holly Anderton

Dr Scott Mueller

A/Prof Kumar Visvanathan

Dr Seth Masters

Dr Alyssa Barry

Dr Matt Firth

Prof Fabienne Mackay

Prof Roger Nation

Ms Madeleine Wemyss

Dr Alice West

A/Prof Michael Gantier

Dr Boris Novakovic

Prof Stephen Kent

Dr Sammy Bedoui

Dr Louis Schofield

Dr Marina Harper